Abstract. Starch is a natural polymer which possesses many alone belongingss and some shortcoming at the same time. Some man-made polymers are biodegradable and can be bespoke easy. Therefore. by uniting the single advantages of amylum and man-made polymers. starch-based wholly biodegradable polymers ( SCBP ) are possible for applications in biomedical and environmental Fieldss. Therefore it received great attending and was extensively investigated. In this paper. the construction and features of amylum and some man-made degradable polymers are briefly introduced. Then. the recent advancement about the readying of SCBP via physical blending and chemical alteration is reviewed and discussed. At last. some illustrations have been presented to clarify that SCBP are assuring stuffs for assorted applications and their development is a good solution for cut downing the ingestion of crude oil resources and environmental job. Keyword: biodegradable polymers. amylum. biopolymer. readying. application
As good known. man-made polymer stuffs have been widely used in every field of human activity [ 1 ] during last decennaries. i. e. post-Staudinger times. These unreal macromolecular substances are normally arising from crude oil and most of the conventional 1s are regarded as non-degradable. However. the crude oil resources are limited and the blooming usage of non-biodegradable polymers has caused serious environmental jobs. In add-on. the non-biodegradable polymers are non suited for impermanent usage such as suturas. Therefore. the polymer stuffs which are degradable and/or biodegradable have being paid more and more attending since 1970s. Both man-made polymers and natural polymers that contain hydrolytically or enzymatically labile bonds or groups are degradable. The advantages of man-made polymers are obvious. including predictable belongingss. batch-to-batch uniformity and
can be tailored easy [ 2 ] . In malice of this. they are rather expensive. This reminds us to concentrate on natural polymers. which are inherently biodegradable [ 3 ] and can be assuring campaigners to run into different demands. Among the natural polymers. amylum is of involvement. It is regenerated from C dioxide and H2O by photosynthesis in workss [ 4 ] . Owing to its complete biodegradability [ 5 ] . low cost and renewability [ 6 ] . amylum is considered as a promising campaigner for developing sustainable stuffs. In position of this. amylum has been having turning attending since 1970s [ 7. 8 ] . Many attempts have been exerted to develop starch-based polymers for conserving the petrochemical resources. cut downing environmental impact and seeking more applications [ 9–11 ] . In this paper. the position of readying and applications of starch-based wholly biodegradable ( SCBP ) polymers is reviewed and presented.
2. Structure and belongingss of amylum
Starch is chiefly composed of two homopolymers of D-glucose [ 8 ] : amylase. a largely additive ?D ( 1. 4’ ) -glucan and branched amylopectin. holding the same anchor construction as amylose but with many ?-1. 6’-linked subdivision points ( Figure 1 ) . There are a batch of hydroxyl groups on amylum ironss. two secondary hydroxyl groups at C-2 and C-3 of each glucose residue. every bit good as one primary hydroxyl group at C-6 when it is non linked. Obviously. amylum is hydrophilic. The available hydroxyl groups on the amylum chains potentially exhibit responsiveness particular for intoxicants.
In other words. they can be oxidized and reduced. and may take part in the formation of H bonds. quintessences and esters [ 12 ] . Starch has different proportions of amylose and amylopectin ranging from about 10–20 % amylose and 80–90 % amylopectin depending on the beginning [ 13 ] . Amylose is soluble in H2O and forms a coiling construction [ 14 ] . Starch occurs of course as distinct granules since the short branched amylopectin ironss are able to organize coiling constructions which crystallize. Starch granules exhibit hydrophilic belongingss and strong inter-molecular association via H bonding formed by the hydroxyl groups on the granule surface. Owing to its hydrophilicity. the internal interaction and morphology of amylum will be readily changed
by H2O molecules. and thereby its glass passage temperature ( Tg ) . the dimension and mechanical belongingss depend on the H2O content. Tg of native amylum can be every bit low as 60 to 80°C when the weight fraction of H2O is in the scope 0. 12 to 0. 14. which allows amylum to be successfully injection moulded to obtain thermoplastic amylum polymers in the presence of H2O [ 15 ] . On the other manus. the hydrophilicity of amylum can be used to better the debasement rate of some degradable hydrophobic polymers. which will be shown in 3. 1. 1. Starch is wholly biodegradable in a broad assortment of environments. It can be hydrolyzed into glucose by micro-organism or enzymes. and so metabolized into C dioxide and H2O [ 16 ] . It is deserving observing that C dioxide will recycle into amylum once more by workss and sunlight. Starch itself is hapless in processability. besides hapless in the dimensional stableness and mechanical belongingss for its terminal merchandises [ 17 ] . Therefore. native amylum is non used straight.
3. Preparation of starch-based biodegradable polymers
To better the belongingss of amylum. assorted physical or chemical alterations of amylum such as blending. derivation and transplant copolymerization have been investigated.
3. 1. Physical blends 3. 1. 1. Blend with man-made degradable polymers At first. amylum was adopted as a filler of polyolefin by Griffin [ 18 ] and its concentrations is every bit low as 6–15 % . Attempts to heighten the biodegradability of the vinyl polymers have been investigated by integrating amylum to a carbon-carbon anchor matrix [ 19 ] . In all these instances starch granules were used to increase the surface country available for onslaught by micro-organism. However. such a system is partly biodegradable and non acceptable from an ecological point of position. Therefore. the blends of amylum and polyolefin will non be mentioned any more in this article. To fix wholly biodegradable starch-based complexs by this scheme. biodegradable polymers are assumed. Normally. the constituents to intermix with amylum are aliphatic polyesters. polyvinyl intoxicant ( PVA ) and biopolymers. The normally used polyesters are poly ( ?-hydroxyalkanoates ) ( PHA ) . obtained by microbic synthesis. and polylactide ( PLA ) or poly ( ?-caprolactone ) ( PCL ) . derived from chemical polymerisation.
The end of intermixing wholly degradable polyester with low cost amylum is to better its cost fight whilst keeping other belongingss at an acceptable degree [ 20. 21 ] . PLA is one of the most of import biodegradable polyesters with many first-class belongingss and has been widely applied in many Fieldss. particularly for biomedical one. PLA possesses good biocompatibility and processability. every bit good as high strength and modulus. However. PLA is really brickle under tenseness and crook tonss and develops serious physical aging during application. Furthermore. PLA is a much more expensive stuff than the common industrial polymers [ 22 ] . Many attempts have been made to develop PLA/ amylum blends to cut down entire natural stuffs cost and heighten their degradability.
The major job of this blend system is the hapless interfacial interaction between hydrophilic amylum granules and hydrophobic PLA. Mechanical belongingss of blends of PLA and amylum utilizing conventional procedures are really hapless because of mutual exclusiveness [ 23 ] . In order to better the compatibility between hydrophilic amylum granules and hydrophobic PLA. glycerin. formamide. and H2O are used entirely or combined as plasticisers to heighten the scattering and the interfacial affinity in thermoplastic amylum ( TPS ) / PLA blends. In the presence of H2O and other plasticisers including glycerin. sorbitol. urea. and formamide [ 24 ] . the strong intermolecular and intramolecular H bonds in amylum can be weakened. To better the compatibility between PLA and amylum. suited compatibilizer should be added. Besides. gelatinization of amylum is besides a good method to heighten the interfacial affinity.
Starch is gelatinized to disintegrate granules and get the better of the strong interaction of amylum molecules in the presence of H2O and other plasticisers. which leads to well scattering [ 25. 26 ] . The glass passage temperature and mechanical belongingss of TPS/PLA blend depend on its composing and the content of plasticiser as good ( Table 1 ) . bespeaking the compatibility between PLA and TPS is low but some grade of interaction is formed [ 26 ] . PCL is another of import member of man-made biodegradable polymer household. It is additive. hydrophobic. partly crystalline polyester. and can be easy degraded by bugs [ 27–29 ] . Blends between amylum and PCL have been good documented in the literatures [ 30–35 ] . The failing of pure amylum stuffs including low resiliency. high wet sensitiveness and high shrinking has been overcome by adding PCL to starch matrix even at low PCL concentration.
The glass passage temperature and mechanical belongingss of TPS/PCL blend are varied with its composing and the content of plasticiser ( Table 2 ) [ 32 ] . As can be seen. TPS/PCL blend is similar to TPS/PLA blend in both the compatibility and the function of constituents. PCL/starch blends can be farther reinforced with fibre and nano-clay severally. Furthermore. the other belongingss of the blends such as hydrolytic stableness. debasement rate. and compatibilization between PCL and amylum are besides improved [ 34. 35 ] . PVA is a man-made water-soluble and biodegradable polymer [ 36 ] . PVA has first-class mechanical belongingss and compatibility with amylum. PVA/ starch blend is assumed to be biodegradable since both constituents are biodegradable in assorted microbic environments. The biodegradability of blends dwelling of amylum. PVA. glycerin and carbamide is performed by bacteriums and Fungis isolated from the activated sludge of a municipal sewerage works and landfill. which indicate that micro-organisms consumed amylum and the formless part of PVA every bit good as the plasticisers [ 37 ] .
Meanwhile. the blend is expected to exhibit good mechanical and procedure belongingss [ 38. 39 ] . Owing to the strong interaction among hydroxyl groups on PVA and amylum ironss. all the Tg of the starch/PVA blends of different composings are lower than that of PVA. The first-class compatibility of two constituents make the tensile strength of the blend increases with increasing PVA concentration. and the elongation at interruption of the blend is about unbroken changeless [ 37 ] . In add-on. PVA can be used to heighten the compatibility of starch/PLA blends. Because both amylum and PVA are polyols. amylum will organize uninterrupted stage with PVA during intermixing. As a consequence. the mechanical belongingss of the starch/PLA blends are improved in the presence of PVA [ 40 ] . As for the blend system without PVA. amylum acts as filler in the PLA uninterrupted matrix.
PLA acts as the chief supporting stage because of the weak interaction between amylum and PLA. 3. 1. 2. Blend with biopolymers Natural polymers such as chitosan and cellulose and their derived functions are inherently biodegradable. and exhibit alone belongingss. A figure of probes have been devoted to analyze the blend of them with amylum. Starch and chitosan are abundant of course happening polyose. Both of them are inexpensive. renewable. non-toxic. and biodegradable [ 41 ] . The starch/chitosan blend exhibits good movie organizing belongings. which is attributed to the inter- and intramolecular H adhering that formed between amino groups and hydroxyl groups on the anchor of two constituents. The mechanical belongingss. H2O barrier belongingss. and miscibility of biodegradable blend movies are affected by the ratio of amylum and chitosan [ 42 ] .
Bulge of the mixture of maize amylum and microcrystalline cellulose in the presence or absence of plasticisers ( polyols ) is used to bring forth comestible movies [ 43 ] . By increasing the content of the cellulose constituent. the rupture strength is increased. whereas the elongation at interruption and the permeableness of movies for H2O vapour are decreased. Starch can organize thermodynamically compatible blend movies with water-soluble carboxymethylcellulose ( CMC ) when the amylum content is below 25 mass % [ 44 ] . Such movies are biodegradable in presence of micro-organisms. Starch-based nanocomposite movie is obtained by projecting the mixture of plasticized amylum and flax cellulose nanocrystals.
4. Applications of starch-based biodegradable polymers 4. 1. In nutrient industry Food packaging and comestible movies are two major applications of the starch-based biodegradable polymers in nutrient industry. The demands for nutrient packaging include cut downing the nutrient losingss. maintaining nutrient fresh. heightening organoleptic features of nutrient such as visual aspect. olfactory property. and spirit. and supplying nutrient safety [ 60 ] . Traditional nutrient packaging stuffs such as LDPE have the job of environmental pollution and disposal jobs [ 61 ] . The starchbased biodegradable polymers can be a possible option for nutrient packaging to get the better of these disadvantages and maintain the advantages of traditional packaging stuffs. However. the constituents in the conventional starch-based polymer packaging stuffs are non wholly inert. The migration of substances into the nutrient perchance happens. and the constituent that migrates into nutrient may do injury for the human organic structure.
In position of this. new starch-based packaging stuffs are being developed. For case. a starch/clay nanocomposite nutrient packaging stuff is developed. which can offer better mechanical belongings and lower migration of polymer and additives [ 62 ] . Starch-based comestible movies are odourless. tasteless. colorless. non-toxic. and biodegradable. They display really low permeableness to oxygen at low comparative humidness [ 63 ] and are proposed for nutrient merchandise protection to better quality and shelf life without impairing consumer acceptableness [ 64 ] . In add-on. amylum can be transformed into a foamed stuff by utilizing H2O steam to replace the polystyrene froth as packaging stuff. It can be pressed into trays or disposable dishes. which are able to fade out in H2O and go forth a non-toxic solution. so can be consumed by microbial environment [ 65 ] . Obviously. the starch-based biodegradable polymers are attractive for nutrient industry and will do great advancement in the hereafter.
3. 2. Chemical derivatives One job for starch-based blends is that amylum and many polymers are immiscible. which leads to the mechanical belongingss of the starch/polymer blends by and large become hapless. Thus. chemical
schemes are taken into consideration. Chemical alterations of amylum are by and large carried out via the reaction with hydroxyl groups in the amylum molecule [ 46 ] . The derived functions have physicochemical belongingss that differ significantly from the parent amylum but the biodegradability is still maintained. Consequently. replacing the hydroxyl groups with some groups or ironss is an effectual agencies to fix starch-based stuffs for assorted demands. Graft copolymerization is an frequently used powerful agencies to modify the belongingss of amylum. Furthermore. starch-g-polymer can be used as an effectual compatibilizer for starch-based blends [ 47–49 ] . PCL and PLA are chemically bonded onto amylum and can be used straight as thermoplastics or compatibilizer. The graft-copolymers starch-g-PCL and starch-g-PLA can be wholly biodegraded under natural conditions and exhibit improved mechanical public presentations. To present PCL or PLA sections onto amylum. the pealing gap transplant polymerisation of ?-caprolactone or L-lactide with amylum is carried out [ 17. 31. 50. 51 ] . Starch-g-poly ( vinyl intoxicant ) can be prepared via the extremist transplant copolymerization of amylum with vinyl ethanoate and so the saponification of the starch-g-poly ( vinyl ethanoate ) . Starch-g-PVA behaves good belongingss of both constituents such as processability. hydrophilicity. biodegradability and gelation ability [ 52–56 ] . Starch can be easy transformed into an anionic polyose via chemical functionalization [ 57 ] . For case. a carboxylic derived function of amylum. maleic starch half-ester acid ( MSA ) . has been prepared via the esterification of amylum with maleic anhydride in the presence of pyridine [ 58 ] . MSA is an anionic polyelectrolyte. accordingly it can execute ionic self-assembly with chitosan in aqueous solution and forms a polysaccharide-based polyelectrolyte complex [ 59 ] .
4. 2. In agribusiness
Starch-based biodegradable polymers have found three major applications in agribusiness: the covering of nursery. mulch movie and fertilisers con-
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trolled release stuffs [ 66 ] . The ingestion of agribusiness movies is abundant. By and large. the disposal methods of tradition movies are landfill. recycling or firing. But they are time-consuming. non economic and lead to environmental pollution [ 67 ] . On the other manus. the utilization efficiency of fertilisers is the cardinal component of the development of agricultural productions. However. due to come up overflow. leaching and vaporisation. the fertilisers escape to environment to do diseconomy and environmental jobs [ 68. 69 ] . The development of starch-based biodegradable polymers offers a possibility to get the better of the mentioned jobs. They can be used as the fertilisers controlled release matrices to let go of the fertilisers easy or in controlled manner. As a consequence. the loss of fertilisers and environment pollution can be avoided or reduced [ 50. 70 ] . After utilizing. starch-based movies can be ploughed into dirt and disposed straight. Furthermore. no toxic residues formed after the debasement of starchbased biodegradable polymers [ 71. 72 ] . Therefore. the development of starch-based stuffs for agribusiness applications is being continued. For illustration. to heighten the mechanical belongingss and dissolver or gas opposition. starch-based biodegradable stuffs are assorted with some nano-grade additives such as TiO2. layered silicate and MMT to organize bionanocomposites [ 73–75 ] .
Figure 2. SEM exposure of strach-g-PVA/HA hydrogel ( scale saloon 3 µm )
4. 3. In medical field
Starch-based biodegradeable polymers have some advantages to be medical polymer stuffs [ 76–81 ] : a ) good biocompatibility B ) biodegradable and its debasement merchandises are non-toxic degree Celsius ) proper mechanical belongingss d ) debasement as requirement Starch-based biodegradeable polymers have been widely investigated in bone tissue technology. Starch-based biodegradable bone cements can supply immediate structural support and degrade from the site of application. Furthermore. they can be combined with bioactive atoms. which allow new bone growing to be induced in both the interface of cement-bone and the volume left by polymer debasement [ 82 ] . In add-on. starch-based biode-
gradeable polymer can besides be used as bone tissue technology scaffold [ 83 ] . Starch-based biodegradable polymers. in the signifier of microsphere or hydrogel. are suited for drug bringing [ 84. 85 ] . There is no demand for surgical remotion of the device after drug depletion. The alone belongingss. such as hydrophilicity. permeableness. biocompatibility. and to some extent similar to soft biological systems. of starch-based hydrogels make them utile for assorted biomedical applications [ 86 ] . The 3D construction of starch-based hydrogels enable them absorb and reserve a plentifulness of H2O and maintain good plenty mechanical belongings at the same clip. Starch-based hydrogels have received growing involvement for biomedical applications. In our lab. physically cross-linked starch-gPVA and starch-g-PVA/hydroxyapatite hydrogel are obtained via repeated freezing/thawing circles. and hydroxyapatite ( HA ) can be good dispersed in such a matrix ( Figure 2 ) [ 55. 87 ] . The H2O content in the fresh starch-g-PVA/HA hydrogel is comparable to that of PVA/HA hydrogel. and the dried starch-g-PVA/HA movies can re-adsorb H2O shortly and make swelling equilibrium within 12 proceedingss.
Starch is renewable from C dioxide. H2O and sunlight. It is biodegradable. inexpensive and to be physical or chemical modified easy. This means someday it is unneeded to trust on crude oil to fix polymers. people may ‘plant’ polymers of suited public presentations from the Earth. and the environmental jobs will be no longer every bit terrible as today. At present and in the close hereafter. different physical and chemical attacks are effectual schemes to develop starch-based wholly biodegradable polymers of appropriate biocompatibility. debasement rate and physical belongingss for assorted applications.
[ 1 ] Vert M. . Santos I. D. . Ponsart S. . Alauzet N. . Morgat J-L. . Coudance J. .
Garreau H. : Degradable polymers in a life environment: Where do you stop up? Polymer International. 51. 840–844 ( 2002 ) . Department of the interior: 10. 1002/pi. 903 [ 2 ] Nair L. S. . Laurencin C. T. : Biodegradable polymers as biomaterials. Advancement in Polymer Science. 32. 762–798 ( 2007 ) . Department of the interior: 10. 1016/j. progpolymsci. 2007. 05. 017 [ 3 ] Chiellini E. . Solaro R. : Biodegradable polymeric stuffs. Advanced Materials. 4. 305–313 ( 1996 ) . Department of the interior: 10. 1002/adma. 19960080406 [ 4 ] Teramoto N. . Motoyama T. . Yosomiya R. . Shibata M. : Synthesis. thermic belongingss. and biodegradability of propyl-etherified amylum. European Polymer Journal. 39. 255–261 ( 2003 ) . Department of the interior: 10. 1016/S0014-3057 ( 02 ) 00199-4 [ 5 ] Araujo M. A. . Cunha A. . Mota M. : Enzymatic debasement of starch-based thermoplastic compounds used in protheses: Designation of the debasement merchandises in solution. Biomaterials. 25. 2687–2693 ( 2004 ) . Department of the interior: 10. 1016/j. biomaterials. 2003. 09. 093 [ 6 ] Zhang J-F. . Sun X. Z. : Mechanical belongingss of PLA/starch complexs compatibilized by maleic anhydride. Biomacromolecules. 5. 1446–1451 ( 2004 ) . Department of the interior: 10. 1021/bm0400022 [ 7 ] Griffin G. J. L. : Starch polymer blends. Polymer Degradation and Stability. 45. 241–247 ( 1994 ) . Department of the interior: 10. 1016/0141-3910 ( 94 ) 90141-4 [ 8 ] Pareta R. . Edirisinghe M. J. : A fresh method for the readying of amylum movies and coatings. Carbohydrate Polymer. 63. 425–431 ( 2006 ) . Department of the interior: 10. 1016/j. carbpol. 2005. 09. 018 [ 9 ] Park J. S. . Yang J. H. . Kim D. H. . Lee D. H. : Degradability of expanded starch/PVA blends prepared utilizing Ca carbonate as the spread outing inhibitor. Journal of Applied Polymer Science. 93. 911–919 ( 2004 ) . Department of the interior: 10. 1002/app. 20533 [ 10 ] Schwach E. . Averous L. : Starch-based biodegradable blends: Morphology and interface belongingss. Polymer International. 53. 2115–2124 ( 2004 ) . Department of the interior: 10. 1002/pi. 1636
[ 11 ] Stepto R. F. T. : Understanding the processing of thermoplastic amylum. Macromolecular Symposia. 245– 246. 571–577 ( 2006 ) . Department of the interior: 10. 1002/masy. 200651382 [ 12 ] Tomasik P. . Schilling C. H. : Chemical alteration of amylum. Progresss in Carbohydrate Chemistry and Biochemistry. 59. 175–403 ( 2004 ) . Department of the interior: 10. 1016/S0065-2318 ( 04 ) 59005-4 [ 13 ] Ramesh M. . Mitchell J. R. . Harding S. E. : Amylose content of rice amylum. Starch. 51. 311–313 ( 1999 ) . Department of the interior: 10. 1002/ ( SICI ) 1521-379X ( 199909 ) 51:8/93. 0. CO ; 2-E [ 14 ] Wallace R. A. . King J. L. . Sanders G. P. : Biology- The scientific discipline of life. Goodyear Printing Company. California ( 1981 ) . [ 15 ] Stepto R. F. T. : The
processing of amylum as a thermoplastic. Macromolecular Symposia. 201. 203–212 ( 2003 ) . Department of the interior: 10. 1002/masy. 200351123 [ 16 ] Primarini D. . Ohta Y. : Some enzyme belongingss of natural amylum digesting amylases from streptomyces sp. No. 4. Starch. 52. 28–32 ( 2000 ) . Department of the interior: 10. 1002/ ( SICI ) 1521-379X ( 200001 ) 52:13. 0. CO ; 2-J [ 17 ] Choi E-J. . Kim C-H. . Park J-K. : Synthesis and word picture of starch-g-polycaprolactone copolymer. Macromolecules. 32. 7402–7408 ( 1999 ) . Department of the interior: 10. 1021/ma981453f [ 18 ] Griffin G. J. L. : Biodegradable man-made rosin sheet stuff incorporating amylum and a fatty stuff. U. S. Patent: 4016117. USA ( 1977 ) . [ 19 ] Bikiaris D. . Prinos J. . Koutsopoulos K. . Vouroutzis N. . Pavlidou E. . Frangis N. . Panayiotou C. : LDPE/ plasticized starch blends incorporating PE-g-MA copolymer as compatibilizer. Polymer Degradation and Stability. 59. 287–291 ( 1998 ) . Department of the interior: 10. 1016/S0141-3910 ( 97 ) 00126-2 [ 20 ] Mani R. . Bhattacharya M. : Properties of injection moulded blends of amylum and modified biodegradable polyesters. European Polymer Journal. 37. 515–526 ( 2001 ) . Department of the interior: 10. 1016/S0014-3057 ( 00 ) 00155-5 [ 21 ] Ratto J. A. . Stenhouse P. J. . Auerbach M. . Mitchell J. . Farrell R. : Processing. public presentation and biodegradability of a thermoplastic aliphatic polyester/starch system. Polymer. 40. 6777–6788 ( 1999 ) . Department of the interior: 10. 1016/S0032-3861 ( 99 ) 00014-2 [ 22 ] Jun C. L. : Reactive blending of biodegradable polymers: PLA and amylum. Journal of Polymers and the Environment. 8. 33–37 ( 2000 ) . Department of the interior: 10. 1023/A:1010172112118 [ 23 ] Wang N. . Yu J. G. . Chang P. R. . Ma X. : Influence of formamide and H2O on the belongingss of thermoplastic starch/poly ( lactic acid ) blends. Carbohydrate Polymers. 71. 109–118 ( 2008 ) . Department of the interior: 10. 1016/j. carbpol. 2007. 05. 025
Lu et Al. – eXPRESS Polymer Letters Vol. 3. No. 6 ( 2009 ) 366–375
[ 24 ] Wang N. . Yu J. G. . Ma X. F. : Preparation and word picture of compatible thermoplastic dry starch/ poly ( lactic acid ) . Polymer Composites. 29. 551–559 ( 2008 ) . Department of the interior: 10. 1002/pc. 20399 [ 25 ] Park J. W. . Im S. S. . Kim S. H. . Kim Y. H. : Biodegradable polymer blends of poly ( L-lactic acid ) and gelatinized amylum. Polymer Engineer and Science. 40. 2539–2550 ( 2000 ) . Department of the interior: 10. 1002/pen. 11384 [ 26 ] Martin O. . Averous L. : Poly ( lactic acid ) :
Plasticization and belongingss of biodegradable multiphase systems. Polymer. 42. 6209–6219 ( 2001 ) . Department of the interior: 10. 1016/S0032-3861 ( 01 ) 00086-6 [ 27 ] Scott G. . Gilead D. : Degradable polymers: Principles and applications. Chapman and Hall. London ( 1995 ) . [ 28 ] Pitt C. G. . Gratzl M. M. . Jeffcoat A. R. . Zweidinger R. A. . Schindler A. : Sustained drug bringing systems II: Factors impacting release rates from poly ( ?-caprolactone ) and related biodegradable polyesters. Journal of Pharmaceutical Sciences. 68. 1534–1538 ( 1979 ) . Department of the interior: 10. 1002/jps. 2600681219 [ 29 ] Li S. M. . Espartero J. L. . Foch P. . Vert M. : Structural word picture and hydrolytic debasement of Zn metal initiated copolymer of L-lactide and ?-caprolactone. Journal of Biomaterials Science. Polymer Edition. 8. 165–187 ( 1997 ) . Department of the interior: 10. 1163/156856296X00237 [ 30 ] Vikman M. . Hulleman S. H. D. . new wave der Zee M. . Myllarinen P. . Feil H. : Morphology and enzymatic debasement of thermoplastic starch-polycaprolactone blends. Journal Applied Polymer Science. 74. 2594– 2604 ( 1999 ) . Department of the interior: 10. 1002/ ( SICI ) 1097-4628 ( 19991209 ) 74:11 3. 0. CO ; 2-R [ 31 ] Dubois P. . Krishnan M. . Narayan R. : Aliphatic polyester grafted starch-like polyoses by ring-opening polymerisation. Polymer. 40. 3091–3100 ( 1999 ) . Department of the interior: 10. 1016/S0032-3861 ( 98 ) 00110-4 [ 32 ] Averous L. . Moro L. . Dole P. . Fringant C. : Properties of thermoplastic blends: Starch-polycaprolactone. Polymer. 41. 4157–4167 ( 2000 ) . Department of the interior: 10. 1016/S0032-3861 ( 99 ) 00636-9 [ 33 ] Singh R. P. . Pandey J. K. . Rutot D. . Degee Ph. . Dubois Ph. : Biodegradation of poly ( ?-caprolactone ) / amylum blends and complexs in composting and civilization environments: The consequence of compatibilization on the built-in biodegradability of the host polymer. Carbohydrate Research. 338. 1759–1769 ( 2003 ) . Department of the interior: 10. 1016/S0008-6215 ( 03 ) 00236-2 [ 34 ] di Franco C. R. . Cyras V. P. . Busalmen J. P. . Ruseckaite R. A. . Vazquez A. : Degradation of polycaprolactone/starch blends and complexs with sisal fiber. Polymer Degradation and Stability. 86. 95–103 ( 2004 ) . Department of the interior: 10. 1016/j. polymdegradstab. 2004. 02. 009
[ 35 ] Vertuccio L. . Gorrasi G. . Sorrentino A. . Vittoria V. : Nano clay reinforced PCL/starch blends obtained by high energy ball milling. Carbohydrate Polymers. 75. 172–179 ( 2009 ) . Department of the interior: 10. 1016/j. carbpol. 2008. 07. 020 [ 36 ] Chiellini E. . Corti A. . D’Antone S. . Solaro R. : Biodegradation of poly ( vinyl intoxicant ) based stuffs. Advancement
in Polymer Science. 28. 963–1014 ( 2003 ) . Department of the interior: 10. 1016/S0079-6700 ( 02 ) 00149-1 [ 37 ] Tudorachi N. . Cascaval C. N. . Rusu M. . Pruteanu M. : Testing of polyvinyl intoxicant and amylum mixtures as biodegradable polymeric stuffs. Polymer Testing. 19. 785–799 ( 2000 ) . Department of the interior: 10. 1016/S0142-9418 ( 99 ) 00049-5 [ 38 ] Lawton J. W. : Consequence of amylum type on the belongingss of amylum incorporating movies. Carbohydrate Polymers. 29. 203–208 ( 1996 ) . Department of the interior: 10. 1016/0144-8617 ( 96 ) 00028-8 [ 39 ] Haschke H. . Tomka I. . Keilbach A. : Systematic probes on the biological degradability of packing stuff III. New polyvinylalcohol-starch-acetal movies ( in German ) . Monatshefte fur Chemie/ Chemical Monthly. 12. 487–507 ( 1998 ) . Department of the interior: 10. 1007/PL00000106 [ 40 ] Ke T. . Sun X. S. : Starch. poly ( lactic acid ) . and poly ( vinyl intoxicant ) blends. Journal of Polymers and the Environment. 11. 7–14 ( 2003 ) . Department of the interior: 10. 1023/A:1023875227450 [ 41 ] Zhai M. L. . Zhao L. . Yoshii F. . Kume T. : Survey on antibacterial starch/chitosan blend movie formed under the action of irradiation. Carbohydrate Polymer. 57. 83–88 ( 2004 ) . Department of the interior: 10. 1016/j. carbpol. 2004. 04. 003 [ 42 ] Bourtoom T. . Chinnan M. S. : Preparation and belongingss of rice starch-chitosan blend biodegradable movie. LWT-Food Science and Technology. 41. 1633–1641 ( 2008 ) . Department of the interior: 10. 1016/j. lwt. 2007. 10. 014 [ 43 ] Psomiadou E. . Arvanitoyannis I. . Yamamoto N. : Edible movies made from natural resources ; Microcrystalline cellulose ( MCC ) . methylcellulose ( MC ) and maize amylum and polyols-Part 2. Carbohydrate Polymer. 31. 193–204 ( 1996 ) . Department of the interior: 10. 1016/S0144-8617 ( 96 ) 00077-X [ 44 ] Suvorova A. I. . Tyukova I. S. . Trufanova E. I. : Biodegradable starch-based polymeric stuffs. Russian Chemical Reviews. 69. 451–459 ( 2000 ) . Department of the interior: 10. 1070/RC2000v069n05ABEH000505 [ 45 ] Cao X. . Chen Y. . Chang P. R. . Muir A. D. . Falk G. : Starch-based nanocomposites reinforced with flax cellulose nanocrystals. Express Polymer Letters. 2. 502– 510 ( 2008 ) . Department of the interior: 10. 3144/expresspolymlett. 2008. 60 [ 46 ] Bao J. S. . Xing J. . Phillips D. L. . Corke H. : Physical belongingss of octenyl succinic anhydride modified rice. wheat. and potato starches. Journal of Agricultural and Food Chemistry. 51. 2283–2287 ( 2003 ) . Department of the interior: 10. 1021/jf020371u
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[ 47 ] Kiatkamjornwong S. . Mongkolsawat K. . Sonsuk M. : Synthesis and belongings word picture of manioc amylum grafted poly [ acrylamide-co- ( maleic acid ) ] superabsorbent via ?-irradiation. Polymer. 43. 3915– 3924 ( 2002 ) . Department of the interior: 10. 1016/S0032-3861 ( 02 ) 00224-0 [ 48 ] Chen L. . Qiu X. Y. . Xie Z. G. . Hong Z. K. . Sun J. R. . Chen X. S. . Jing X. B. : Poly ( L-lactide ) /starch blends compatibilized with poly ( L-lactide ) -g-starch copolymer. Carbohydrate Polymers. 65. 75–80 ( 2006 ) . Department of the interior: 10. 1016/j. carbpol. 2005. 12. 029 [ 49 ] Choi E-J. . Kim C-H. . Park J-K. : Structure-property relationship in PCL/starch blend compatibilized with starch-g-PCL copolymer. Journal of Polymer Science Part B: Polymer Physics. 37. 2430–2438 ( 1999 ) . Department of the interior: 10. 1002/ ( SICI ) 1099-0488 ( 19990901 ) 37:17 & lt ; 2430: :AID-POLB14 & gt ; 3. 0. CO ; 2-4 [ 50 ] Chen L. . Xie Z. G. . Zhuang X. L. . Chen X. S. . Jing X. B. : Controlled release of urea encapsulated by starchg-poly ( L-lactide ) . Carbohydrate Polymers. 72. 342– 348 ( 2008 ) . Department of the interior: 10. 1016/j. carbpol. 2007. 09. 003 [ 51 ] Xu Q. . Kennedy J. F. . Liu L. J. : An ionic liquid as reaction media in the ring gap transplant polymerisation of ?-caprolactone onto amylum granules. Carbohydrate Polymers. 72. 113–121 ( 2008 ) . Department of the interior: 10. 1016/j. carbpol. 2007. 07. 031 [ 52 ] Fanta G. F. . Burr R. C. . Doane W. M. . Russell C. R. : Graft polymerisation of vinyl ethanoate onto amylum. Saponification to starch-g-poly ( vinyl intoxicant ) . Journal of Applied Polymer Science. 23. 229–240 ( 1979 ) . Department of the interior: 10. 1002/app. 1979. 070230121 [ 53 ] Simi C. K. . Abraham T. E. : Hydrophobic grafted and crosslinked amylum nanoparticles for drug bringing. Bioprocess and Biosystems Engineering. 30. 173–180 ( 2007 ) . Department of the interior: 10. 1007/s00449-007-0112-5 [ 54 ] Samaha S. H. . Nasr H. E. . Hebeish A. : Synthesis and word picture of starch-poly ( vinyl ethanoate ) transplant copolymer and their saponified signifier. Journal of Polymer Research. 12. 343–353 ( 2005 ) . Department of the interior: 10. 1007/s10965-004-7937-2 [ 55 ] Xiao C. M. . Yang M. L. : Controlled readying of physical cross-linked starch-g-PVA hydrogel. Carbohydrate Polymer. 64. 37–40 ( 2006 ) . Department of the interior: 10. 1016/j. carbpol. 2005. 10. 020 [ 56 ] Zhu Z. F. . Zhuo R. X. : Slow release behaviour of starch-g-poly ( vinyl intoxicant ) matrix for 2. 4. 5trichlorophenoxyacetic acerb weedkiller. European Polymer Journal. 37. 1913–1919 ( 2001 ) . Department of the interior: 10. 1016/S0014-3057 ( 01 ) 00055-6 [ 57 ] Grote C. . Lazik W. . Heinze T. : Tartaric acid amylum quintessence: A fresh biopolymer-based polyelectrolyte. Macromolecular Rapid Communications. 24. 927– 931 ( 2003 ) . Department of the interior: 10. 1002/marc. 200300042 [ 58 ] Xiao C. M. . Ye J. : Preparation of the
carboxylic derivates of amylum with maleic anhydride. Chinese Journal of Applied Chemistry. 22. 643–646 ( 2005 ) .
[ 59 ] Xiao C. M. . Fang F. : Ionic self-assembly and word picture of a polysaccharide-based polyelectrolyte composite of maleic amylum half-ester acid with chitosan. Journal of Applied Polymer Science. 112. 2255–2260 ( 2009 ) . Department of the interior: 10. 1002/app. 29763 [ 60 ] Zhao R. X. . Torley P. . Halley P. J. : Emerging biodegradable stuffs: Starch- and protein-based bio-nanocomposites. Journal of Material Science. 43. 3058–3071 ( 2008 ) . Department of the interior: 10. 1007/s10853-007-2434-8 [ 61 ] Ozdemir M. . Floros J. D. : Active nutrient packaging engineerings. Critical Reviews in Food Science and Nutrition. 44. 185–193 ( 2004 ) . Department of the interior: 10. 1080/10408690490441578 [ 62 ] Avella M. . de Vlieger J. J. . Errico M. E. . Fischer S. . Vacca P. . Volpe M. G. : Biodegradable starch/clay nanocomposite movies for nutrient packaging applications. Food Chemistry. 93. 467–474 ( 2005 ) . Department of the interior: 10. 1016/j. foodchem. 2004. 10. 024 [ 63 ] The D. P. . Debeaufort F. . Voilley A. . Luu D. : Biopolymer interactions affect the functional belongingss of comestible movies based on agar. manioc amylum and arabinoxylan blends. Journal of Food Engineering. 90. 548–558 ( 2009 ) . Department of the interior: 10. 1016/j. jfoodeng. 2008. 07. 023 [ 64 ] Flores S. . Haedo A. S. . Campos C. . Gerschenson L. : Antimicrobial public presentation of K sorbate supported in tapioca amylum comestible movies. European Food Research Technology. 225. 375–384 ( 2007 ) . Department of the interior: 10. 1007/s00217-006-0427-5 [ 65 ] Siracusa V. . Rocculi P. . Romani S. . Rosa M. D. : Biodegradable polymers for nutrient packaging: A reappraisal. Tendencies in Food Science and Technology. 19. 634–643 ( 2008 ) . Department of the interior: 10. 1016/j. tifs. 2008. 07. 003 [ 66 ] Dilara P. A. . Briassoulis D. : Degradation and stabilisation of low-density polythene movies used as nursery covering stuffs. Journal of Agricultural Engineering Research. 76. 309–321 ( 2000 ) . Department of the interior: 10. 1006/jaer. 1999. 0513 [ 67 ] Bohlmann G. . Toki G. : Chemical economic sciences enchiridion. SRI International. Menlo Park ( 2004 ) . [ 68 ] Dave A. M. . Mehta M. H. . Aminabhavi T. M. . Kulkarni A. R. . Soppimath K. S. : A reappraisal on controlled release of N fertilisers through polymeric membrane devices. Polymer-Plastics Technology and Engineering. 38. 675–711 ( 1999 ) . Department of the interior: 10. 1080/03602559909351607 [ 69 ] Guo M. . Liu M. . Zhan F. . Wu L. : Preparation and belongingss of a slow-release membrane-encapsulated urea fertiliser with superabsorbent and wet saving. Industrial and
Engineering Chemistry Research. 44. 4206–4211 ( 2005 ) . Department of the interior: 10. 1021/ie0489406
Lu et Al. – eXPRESS Polymer Letters Vol. 3. No. 6 ( 2009 ) 366–375
[ 70 ] Kumbar S. G. . Kulkarni A. R. . Dave A. M. . Aminabha T. M. : Encapsulation efficiency and release dynamicss of solid and liquid pesticides through urea methanal crosslinked amylum. guar gum. and starch + cluster bean gum matrices. Journal of Applied Polymer Science. 82. 2863–2866 ( 2001 ) . Department of the interior: 10. 1002/app. 2141 [ 71 ] Malinconico M. . Immirzi B. . Massenti S. . La Mantia F. P. . Mormile P. . Petti L. : Blends of polyvinylalcohol and functionalised polycaprolactone. A survey on the thaw bulge and post-cure of movies suited for protected cultivation. Journal of Materials Science. 37. 4973–4978 ( 2002 ) . Department of the interior: 10. 1023/A:1021058810774 [ 72 ] Scott G. : ‘Green’ polymers. Polymer Degradation and Stability. 68. 1–7 ( 2000 ) . Department of the interior: 10. 1016/S0141-3910 ( 99 ) 00182-2 [ 73 ] Scarascia-Mugnozza G. . Schettini E. . Vox G. . Malinconico M. . Immirzi B. . Pagliara S. : Mechanical belongingss decay and morphological behavior of biodegradable movies for agricultural mulching in existent scale experiment. Polymer Degradation and Stability. 91. 2801–2808 ( 2006 ) . Department of the interior: 10. 1016/j. polymdegradstab. 2006. 02. 017 [ 74 ] Wang Y-Z. . Yang K-K. . Wang X-L. . Zhou Q. . Zheng C-Y. . Chen Z-F. : Agricultural application and environmental debasement of photo-biodegradable polythene mulching movies. Journal of Polymers and the Environment. 12. 7–10 ( 2004 ) . Department of the interior: 10. 1023/B: JOOE. 0000003122. 71316. 8e [ 75 ] Yew S. P. . Tang H. Y. . Sudesh K. : Photocatalytic activity and biodegradation of polyhydroxybutyrate movies incorporating Ti dioxide. Polymer Degradation and Stability. 91. 1800–1807 ( 2006 ) . Department of the interior: 10. 1016/j. polymdegradstab. 2005. 11. 011 [ 76 ] Marques A. P. . Reis R. L. . Hunt J. A. : The biocompatibility of fresh starch-based polymers and complexs: In vitro surveies. Biomaterials. 23. 1471–1478 ( 2002 ) . Department of the interior: 10. 1016/S0142-9612 ( 01 ) 00272-1 [ 77 ] Mendes S. C. . Reis R. L. . Bovell Y. P. . Cunha A. M. . new wave Blitterswijk C. A. . de Bruijn J. D. : Biocompatibility testing of fresh starch-based stuffs with possible application in orthopedic surgery: A preliminary survey. Biomaterials. 22. 2057–2064 ( 2001 ) . Department of the interior: 10. 1016/S0142-9612 ( 00 ) 00395-1 [ 78 ] Azevedo H. S. .
Gama F. M. . Reis R. L. : In vitro appraisal of the enzymatic debasement of several amylum based biomaterials. Biomacromolecules. 4. 1703–1712 ( 2003 ) . Department of the interior: 10. 1021/bm0300397
[ 79 ] Defaye J. . Wong E. : Structural surveies of gum Arabic. the exudate polyose from acacia Senegal. Carbohydrate Research. 150. 221–231 ( 1986 ) . Department of the interior: 10. 1016/0008-6215 ( 86 ) 80018-0 [ 80 ] Reddy S. M. . Sinha V. R. . Reddy D. S. : Fresh unwritten colon-specific drug bringing systems for pharmacotherapy of peptides and nonpeptide drugs. Drugs of Today. 35. 537–580 ( 1999 ) . [ 81 ] Sinha V. R. . Kumria R. : Polysaccharides in colon-specific drug bringing. International Journal of Pharmaceutics. 224. 19–38 ( 2001 ) . Department of the interior: 10. 1016/S0378-5173 ( 01 ) 00720-7 [ 82 ] Boesel L. F. . Mano J. F. . Reis R. L. : Optimization of the preparation and mechanical belongingss of amylum based partly degradable bone cements. Journal of Materials Science: Materials in Medicine. 15. 73–83 ( 2004 ) . Department of the interior: 10. 1023/B: JMSM. 0000010100. 07715. eb [ 83 ] Gomes M. E. . Sikavitsas V. I. . Behravesh E. . Reis R. L. . Mikos A. G. : Consequence of flow perfusion on the osteogenic distinction of bone marrow stromal cells cultured on starch-based 3-dimensional scaffolds. Journal of Biomedical Materials Research Part A. 67. 87–95 ( 2003 ) . Department of the interior: 10. 1002/jbm. a. 10075 [ 84 ] Balmayor E. R. . Tuzlakoglu K. . Marques A. P. . Azevedo H. S. . Reis R. L. : A fresh enzymaticallymediated drug bringing bearer for bone tissue technology applications: Uniting biodegradable starchbased microparticles and distinction agents. Journal of Material Science: Materials in Medicine. 19. 1617–1623 ( 2008 ) . Department of the interior: 10. 1007/s10856-008-3378-5 [ 85 ] Reis A. V. . Guilherme M. R. . Moia T. A. . Mattoso L. H. C. . Muniz E. C. . Tambourgi E. B. : Synthesis and word picture of a starch-modified hydrogel as possible bearer for drug bringing system. Journal of Polymer Science Part A: Polymer Chemistry. 46. 2567–2574 ( 2008 ) . Department of the interior: 10. 1002/pola. 22588 [ 86 ] Peppas N. A. . Bures P. . Leobandung W. . Ichikawa H. : Hydrogels in pharmaceutical preparations. European Journal of Pharmaceutics and Biopharmaceutics. 50. 27–46 ( 2000 ) . Department of the interior: 10. 1016/S0939-6411 ( 00 ) 00090-4 [ 87 ] Gao Y. K. . Xiao C. M. : Preparation and word picture of starch-g-PVA/nano-hydroxyapatite complex hydrogel. Journal of Wuhan University of Technology-Materials Science Edition. 20. 58–59 ( 2005 ) .