(Immuno-Augmentative Therapy) IAT was developed in the 1960s by Dr. Lawrence Burton at the St. Vincent Hospital in New York City. On the basis of animal experiments Dr. Burton was able to identify and isolate tumor suppressing factors that also were effective with humans. Dr. Burton identified and isolated blood protein components, which he assumed were associated with the occurrence of cancer. These were: Tumor complement (a substance that is developed from the blood clots of cancer patients. This factor, which is also referred to as the C3 complement, then activates 2 tumor antibodies (TA1 and TA2). A fourth protein, the blocking protein factor (DPF), comes from the blood serum of healthy donors. When these 4 blood protein components are in balance, then the body, according to Dr. Burton, should be capable of conquering the cancer on its own. If they are not balanced then the body cannot adequately defend itself. If, for example, too much of the blocking protein is present, the tumor antibodies will be suppressed, and then they are no longer capable of neutralizing cancer cells. Dr. Burton explained that all cells release a blocking protein when they die, which prevents additional activities of the tumor antibodies. Dr. Burton determined that a remission for different types of cancer could be induced when he injected his patients with a certain number of these components. Even for types of cancer which apparently were thought to quickly end in death. However he also declared immediately that his treatment was no cure for cancer. Rather he compared it with insulin for diabetics. It controls the cancer and the patient can live for many more years. Dr. Burton astounded the oncological world in 1966. At a seminar in Phoenix Arizona, he injected his serum into mice with very large tumors. The tumors disappeared within two hours. In the same year he repeated this experiment in front of the skeptical New York Academy of Medicine, whose members doubted the Phoenix experiment and brought their own mice. Here as well the tumors of 16 mice disappeared within two hours. Although a book published by the American government agency, Office of Technology, Unconventional Cancer Therapies, explained that IAT was not able to clearly demonstrate tumor reductions, it did accept the results of a different study (coordinated by Dr. Barrie Cassileth from the University of North Carolina – a critic of alternative cancer therapies and a representative of the American Cancer Society). In this study 79 patients with advanced (metastatizing) cancer were give IAT. 60 patients (63%) survived an average of 65 months (more than 5 years after the diagnosis). The 20 patients who died survived on average 59 months (i.e. almost 5 years). These results were astounding because the normal chances of survival for the majority of these patients was 36 months. Consequently it could be determined that Dr. Burton’s IAT approximately doubled the survival chances as compared with the survival chances of patients treated with conventional cancer therapies. Another study published in 1977 with 277 patients, most of whom had a hopeless prognosis, showed that 18% were still alive after 5 years. This number is also astounding because the one-year survival rate of these patients was less than 1%. As with almost all non-conventional therapies, patients are usually subjected to other conventional treatment methods, and it is only after these have been unsuccessful that patients decide for IAT. Dr. Burton knew this and yet was still able to send 4 – 6 patients out of 10 home with improvement. According to Dr. Burton’s information IAT achieved a tumor reduction or total remission in 40-60% of the patients that he treated. His results were particularly good for people with advanced colon cancer and for mesotheliomas. According to the standard statistics, chances for 5-year survival are zero for these cancer types. Dr. Burton reported on the successful treatment of 11 patients with pleural mesothelioma, a form of cancer (usually triggered by asbestos), which we know is fatal and incurable. The American Medical Association was certainly alarmed about this statement and immediately proclaimed that IAT must be a quack remedy.Patients come into the IAT clinic every morning; they stay in apartments or hotels. In the clinic blood is taken and analyzed every day. After the evaluation a new serum is determined and created daily (a protein from the serum of healthy donors is used, which improves/strengthens the blood of the patient). The patient then leaves the clinic and administers the injections himself in the course of the day. Daily injections are administered for 6-12 weeks. Afterwards the patient can return home where he continues with the injections.